Researchers provide clinical evidence of collagen peptides as anti-ageing nutricosmetic

By Andrew MCDOUGALL contact

- Last updated on GMT

Researchers provide clinical evidence of collagen peptides as anti-ageing nutricosmetic

Related tags: Skin

A team of researchers has shown the efficacy of specific collagen peptides to improve skin moisture and, for the first time, to prevent and reduce the fragmentation of the dermal collagen network, thus counteracting one of the hallmarks of skin ageing.

The study focused on popular collagen peptides brand Peptan and says that the improvement of the physiological skin parameters is likely linked to an increase of collagen and glycosaminoglycan synthesis in the respective skin layers.

The study, published in the Journal of Cosmetic Dermatology​ by a collaboration of scientists in France, Belgium and Japan, says the data demonstrates that the oral supplementation with specific collagen peptides can improve skin structure and health from within.

Collagen study

In the study, two placebo-controlled clinical trials were run to assess the effect of a daily oral supplementation with collagen peptides on skin hydration by corneometry, on collagen density by high-resolution ultrasound and on collagen fragmentation by reflectance confocal microscopy.

Human skin explants were used to study extracellular matrix components in the presence of collagen peptides ex vivo.

The research showed that oral collagen peptide supplementation significantly increased skin hydration after 8 weeks of intake.

The scientists said that collagen density in the dermis significantly increased and the fragmentation of the dermal collagen network significantly decreased already after 4 weeks of supplementation.

Both effects persisted after 12 weeks, and ex vivo​ experiments demonstrated that collagen peptides induce collagen as well as glycosaminoglycan production, offering a mechanistic explanation for the observed clinical effects.

“The oral supplementation with collagen peptides is efficacious to improve hallmarks of skin ageing,”​ say the researchers, from France’s COSderma and 2BIO-EC Laboratoryies, Japan’s Unitec Foods, and Belgian supplier Rousselot.

Skin health nutrition

Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin ageing, and nutrition has often been seen as a key factor influencing skin health and consequently its appearance.

A wide range of dietary supplements is offered to improve skin health, and collagen peptides are used as a bioactive ingredient in nutricosmetic products as they have been shown in preclinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration.

Related products

show more

Sensiva™ go natural,a protector without compromise

Sensiva™ go natural,a protector without compromise

Ashland Global Holdings Inc | 24-Jun-2022 | Technical / White Paper

Consumers are increasingly buying natural, organic beauty and wellbeing products as noted from the increasing number of product launches with natural claim...

Formulating for Clean Beauty

Formulating for Clean Beauty

Elementis | 26-May-2022 | Product Brochure

Water scarcity and water pollution continues to be a concern for the environment. Every year, about 130 tons of microplastic particles from personal care...

Caressense™ biofunctional, powering ageless beauty

Caressense™ biofunctional, powering ageless beauty

Ashland Global Holdings Inc | 01-May-2022 | Data Sheet

For the first time, Ashland researchers reveal a natural bioactive that can activate skin’s sensors of touch, the piezos, to release “feel-good” and anti-aging...

Related suppliers

Follow us

Products

View more

Webinars

Indie Pioneers Podcast

Indie Pioneers Podcast