New elastosome technology boosts EGF penetration for superior anti-ageing results
Researchers in South Korea have developed a high-performance delivery system that pushes large-molecule anti-ageing ingredients deep into the skin.
The research team, representing Inha University Hospital, Humantest Co, and B&B Korea, showed how a novel “elastosome” formulation significantly outperformed traditional liposomes by using a flexible membrane that could squeeze through the skin’s microscopic gaps.
This breakthrough addresses a long-standing hurdle for cosmetic formulators who struggle to make bioactive proteins like epidermal growth factor (EGF) effective in topical creams.
Dry skin linked to systemic lipid imbalance, not simple deficiency: China study
New research from China revealed that low-hydration skin was not simply the result of a lipid shortage, but is characterised by systemic lipidomic dysregulation. This means that the skin overproduces certain lipids in a failed attempt to repair its own barrier.
The research team from Meyer Bio-Medicine Co and Shandong University used advanced non-invasive technologies to map the molecular landscape of the skin.
The findings provide a multi-dimensional look at how skin hydration interacts with the skin’s physical structure and its internal chemical factory, suggesting that the cosmetics industry may need to rethink its approach to treating dry skin.
Kampo-based cream found to reduce eye wrinkles in Japanese clinical trial
A cream formulated with diverse bioactive ingredients derived from Kampo, traditional Japanese herbal medicine, can significantly reduce shallow wrinkles at corners of the eyes in women.
This was the key finding from a clinical study conducted by researchers from Kochi Gakuen University, Mz Science Co Ltd, Shinyamato Kanpoh Pharmaceutical Co Ltd, and Kindai University.
They evaluated the effects of the test cream, dubbed “Gold Hakuyo all-in-one cream”, on 14 healthy female subjects aged 31 to 59, with results highlighting the potential of a multi-ingredient approach, which is characteristic of Kampo, for addressing the complex, varied causes of skin ageing.
Combination therapy shows promise for treating atrophic acne scars in new study
A recent multi-centre study has revealed that a combination of Polynucleotide High-Purification Technology (PN HPT) and hyaluronic acid significantly improved the appearance of moderate to severe atrophic facial acne scars.
The research suggested that this bio-regenerative approach offered a safe and effective alternative to more invasive dermatological procedures.
Researchers from clinics in Malaysia and Italy tracked 62 patients over six months to evaluate the efficacy of a sterile intradermal gel known as Newest. The study participants, who represented both Asian and Caucasian ethnicities, saw measurable reductions in scar severity and reported high levels of satisfaction with the results.
Probiotic-derived phenyllactic acid emerges as potent skin lightening agent: Korea study
A metabolite derived from a common probiotic bacterium, Limosilactobacillus reuteri, has demonstrated powerful and safe skin lightening effects in laboratory tests, positioning it as a promising new ingredient for the functional cosmetics market.
South Korean researchers from Dongshin University and B & Tech Co. found that the postbiotic metabolite, phenyllactic acid (PLA), significantly inhibited melanin production in melanoma cells.
The effects were achieved without any observed toxicity. At a high concentration, PLA proved even more effective than the established cosmetic standard, arbutin.
